(Hypromellose Acetate Succinate)
Shin-Etsu AQOAT® (hypromellose acetate succinate) is our second enteric coating material and it was developed for aqueous coating. Shin-Etsu AQOAT® was approved as a pharmaceutical excipient in Japan in 1987, and then in the United States and several European countries in 2001. In an aqueous system, a suspension containing Shin-Etsu AQOAT® (fine powder), triethyl citrate as a plasticizer, talc as an anti-tacking agent, and sodium lauryl sulfate as a wetting agent is typically used.
Shin-Etsu AQOAT® also shows excellent performance when it is used as a carrier for solid dispersions in order to enhance solubility of poorly soluble drugs.
Shin-Etsu AQOAT® Enteric Coating Agent (Aqueous System & Solvent System)
(Hypromellose Acetate Succinate; NF)
|Grade||pH Solubility||Application Form in Coating Operation|
Note: * F is fine powder grade (av. particle size about 5μm).