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Pharmacoat
(Hypromellose*)
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* |
Instead of Hydroxypropyl
Methylcellulose we changed its generic name to Hypromellose
as from October, 2002. |
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Film coating was developed as an
undercoating for sugar coating in the 1950's and film-coated
tablets were eventually introduced in the early 1970's. Since
then, development work aimed at increasing the production rate
of film-coated tablets and reducing the cost has been done in
order to improve the efficiency of the pharmaceutical product,
as well as the bioavailability of drug. Film coating is now
well-established and an effective technique. "Pharmacoat" was
developed from hydroxypropyl methylcellulose in 1963, during
the early days of film coating. It has been the subject of a
continuous program of development and quality improvement since
then. Film coatings of this type are now in widespread use throughout
the world.
"Pharmacoat" is also effective as a binder, since it does not
interact with drugs, and it has a superior stability, non-ionic
character. In addition, "Pharmacoat" can be used for cellulose
capsule manufacturing instead of gelatin due to its more stable
characteristics. |
Product line-up of Pharmacoat had been revised from June 2007.
Pharmacoat Water-Soluble Film Coating Agent
(Hypromellose; USP) |
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Grade |
Substitution
Type |
Labeled
Viscosity (mPa・s)* |
| Pharmacoat |
603 |
2910 |
3 |
| 645 |
4.5 |
| 606 |
6 |
| 615 |
15 |
| 904 |
2208 |
4 |
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Note: * 2 wt.% aqueous solution
at 20oC according
to the USP measuring method.
Pharmacoat is also useful as a binder for tablets or granules.
Pharmacoat 904 is especially useful as a binder for sugar coating.
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