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Shin-Etsu Chemical Co., Ltd.
Organic Chemicals Division
Cellulose & Pharmaceutical Exciplents Department
Metolose
Types
Grades
Characteristics
Field of applications & Compatible products
Cyanoresin
Type of METOLOSE
  

Types of METOLOSE are divided as shown below according to the type of substituent groups introduced to the cellulose molecules as well as the degree of substitution and molar substitution

Typical degree of substitution and molar substitution for METOLOSE products

Type
SM
SH
SE
60SH
65SH
90SH
SEB
SNB
Chemical name
Methylcellulose
(MC)
Hydroxypropylmethyl
cellulose
(HPMC)
Hydroxyethylmethyl
cellulose
(HEMC)
Degree of substitution
Methoxyl group
(-OCH
3)
1.8
1.9
1.8
1.4
1.5
1.5
Molar substitution
Hydroxypropoxyl group
(-OCH
2CHOHCH3)
-
0.25
0.15
0.20
-
-
Hydroxyethoxyl group
(-OCH
2CH2OH)
-
-
-
-
0.20
0.30
CAS number
9004-67-5
9004-65-3
9032-42-2

* Degree of substitution
     The average number of methoxyl groups attached to the anhydroglucose unit of cellulose
* Molar substitution
     The average number of moles of hydroxylpropoxyl groups or hydroxylethoxyl groups
      per mole of anhydroglucose unit of cellulose
 

(hi METOLOSE)

hi METOLOSE is METOLOSE surface-treated with a little glyoxal. This product can rapidly turn wet and disperse without forming lumps even when added to cold water and then dissolve by continuing agitation. An addition of alkaline ingredients to the dispersion will speed up the dissolving process.
 
 

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